Additional sensitivity analyses.
The influence on the incremental cost-effectiveness ratio of varying mortality RRs and incremental device costs of CRT-D (A), mortality RRs and CRT-D battery lives (B), rates of lead infection (C), and rates of lead failure (D). The solid vertical line represents the base case. CRT-D = cardiac resynchronization therapy combined with an ICD; ICD = implantable cardioverter-defibrillator; QALY = quality-adjusted life-year; RR = risk ratio.