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. Author manuscript; available in PMC: 2021 May 7.
Published in final edited form as: Ann Intern Med. 2015 Sep 15;163(6):417–426. doi: 10.7326/M14-1804

Appendix Table 3.

Comparison of Model Results With Trial Data

Outcome Events/Patients, n/n (%)
Model Results
RAFT Results (12)
MADIT-CRT Results (11)
CRT-D ICD CRT-D ICD CRT-D ICD

Heart failure (29 mo) 124/1089 (11.3) 140/731 (19.1) - - 151/1089(13.9) 167/731 (22.8)
Death (29 mo) 128/1089 (11.8) 108/731 (14.8) - - 74/1089(6.8) 53/731 (7.3)
Heart failure hospitalization (40 mo) 123/708 (17.3) 174/730 (23.8) 115/708(16.2) 159/730 (21.8) - -
Death (40 mo) 117/708 (16.5) 150/730 (20.5) 110/708(15.5) 154/730 (21.1) - -

CRT-D = cardiac resynchronization therapy combined with an ICD; ICD = implantable cardioverter-defibrillator; MADIT-CRT = Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy; RAFT = Resynchronization-Defibrillation for Ambulatory Heart Failure Trial.