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. Author manuscript; available in PMC: 2021 May 7.
Published in final edited form as: Ann Intern Med. 2015 Sep 15;163(6):417–426. doi: 10.7326/M14-1804

Table 2.

Health and Economic Outcomes of CRT-D versus ICD

Variable CRT-D ICD

Adverse events
 Heartfailure hospitalizations per patient 0.9 1.1
 Generator changes per patient 3.1 2.2
 Lead failures per patient 0.3 0.2
 Lead infections per patient 0.1 0.1
LYs 9.8 8.8
QALYs 8.6 7.6
Lifetime costs, $ 286 500 228 600
Incremental cost perLY and QALY gained
versus ICD, $
 Cost/LY gained 59 500/LY -
 Cost/QALY gained 61 700/QALY -

CRT-D = cardiac resynchronization therapy combined with an implantable cardioverter-defibrillator; ICD = implantable-cardioverter defibrillator; LY = life-year; QALY = quality-adjusted life-year.