Table 3.
The significant enriched GO pathways from GSEA results (∗∗P < 0.01, FDR < 0.25).
| Term_ranked | Term | ES | NES | P value | FDR | Geneset_size | Matched_size |
|---|---|---|---|---|---|---|---|
| 1 | Muscle contraction (GO: 0006936) | 0.872 | 1.669 | 0 | 0 | 51 | 46 |
| 2 | Sarcomere organization (GO: 0045214) | 0.883 | 1.658 | 0 | 0.001 | 39 | 33 |
| 3 | Myofibril (GO: 0030016) | 0.886 | 1.654 | 0 | 0.001 | 41 | 31 |
| 4 | Oogenesis (GO: 0048477) | 0.879 | 1.632 | 0 | 0.002 | 38 | 27 |
| 5 | Regulation of muscle contraction (GO: 0006937) | 0.892 | 1.623 | 0 | 0.002 | 22 | 20 |
| 6 | Z disc (GO: 0030018) | 0.79 | 1.594 | 0 | 0.007 | 122 | 98 |
| 7 | Condensed nuclear chromosome (GO: 0000794) | 0.827 | 1.583 | 0 | 0.012 | 43 | 38 |
| 8 | Striated muscle thin filament (GO: 0005865) | 0.904 | 1.577 | 0 | 0.014 | 21 | 16 |
| 9 | Myosin complex (GO: 0016459) | 0.818 | 1.573 | 0 | 0.015 | 47 | 37 |
| 10 | A band (GO:0031672) | 0.879 | 1.564 | 0 | 0.022 | 22 | 18 |
| 11 | M band (GO: 0031430) | 0.882 | 1.562 | 0.001 | 0.022 | 24 | 17 |
| 12 | Synaptonemal complex (GO: 0000795) | 0.859 | 1.541 | 0 | 0.045 | 29 | 22 |
| 13 | Structural constituent of cytoskeleton (GO: 0005200) | 0.779 | 1.535 | 0 | 0.05 | 71 | 59 |
| 14 | I band (GO: 0031674) | 0.869 | 1.535 | 0 | 0.052 | 23 | 20 |
| 15 | Striated muscle contraction (GO: 0006941) | 0.881 | 1.526 | 0.001 | 0.064 | 23 | 16 |
| 16 | Cardiac muscle tissue morphogenesis (GO: 0055008) | 0.863 | 1.51 | 0.006 | 0.103 | 18 | 16 |
| 17 | Structural constituent of muscle (GO: 0008307) | 0.845 | 1.507 | 0.001 | 0.109 | 28 | 22 |
| 18 | Microtubule-based process (GO: 0007017) | 0.798 | 1.505 | 0.004 | 0.107 | 35 | 31 |
| 19 | Skeletal muscle fiber development (GO: 0048741) | 0.831 | 1.503 | 0.002 | 0.106 | 27 | 22 |
| 20 | Cardiac muscle contraction (GO: 0060048) | 0.797 | 1.501 | 0 | 0.111 | 50 | 40 |