A. Male WT mice were gavage fed with different doses of TPI, aspirin, and clopidogrel in saline for one week and then subjected to the 7.5% FeCl3-induced thrombosis model. WT male mice received saline were used as control. B. Representative video images for mice received 1 mg/kg TPI, 1 mg/kg aspirin, and 2.5 mg/kg clopidogrel are shown. C. Bleeding times in mice received aspirin (1.0 mg/kg), clopidogrel (2.5 mg/kg), and TPI (0.5 and 1 mg/kg) were compared with WT mice without ant treatment. * p<0.05, ** p<0.005, and **** p<0.0001 vs. WT. † p<0.005 vs. TPI 0.5 mg/kg.