Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Plot showing lipophilicity (i.e., logD7.4), acidity (i.e., pKa), and permeability (i.e., logPapp) of test compounds. Each of the four reference compounds (structures shown) and their corresponding analogs are identified with different symbols.
