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. 2021 May 7;12(5):457. doi: 10.1038/s41419-021-03722-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — SW620 cells with stable YAP overexpression (YAP), knocking down of YAP (shYAP), or control cells (Blank) were subcutaneously injected into nude mice. A Tumor size and D body weight of the mice were measured twice a week. B Tumor tissues were collected from the sacrificed mice nearly 5 weeks after injection of the cells, and C weights of the formed tumors were measured for statistic analysis. E The expressions of YAP and LC3B in the tumor tissues were measured by western blot, using GAPDH as a loading control. F The expression of YAP and Bcl-2 in the tumor tissues was detected by IHC. Data represent mean ± SD. *P < 0.05, **P < 0.01.