Table 4.

Sub-analysis: volume of largest metastasis.

Model	C-Index (95% CI)
Largest metastasis < 0.200 cc (n = 261)
Unweighted average	0.674 (0.630–0.729)
Weighted average	0.694 (0.639–0.749)
Weighted average of largest 3	0.701 (0.652–0.748)
Largest + number of metastases	0.698 (0.644–0.767)
Largest	0.695 (0.634–0.736)
Smallest	***
Largest metastasis 0.200–0.700 cc (n = 281)
Unweighted Average	0.663 (0.615–0.719)
Weighted average	0.675 (0.622–0.731)
Weighted average of largest 3	0.687 (0.622–0.728)
Largest + number of metastases	0.668 (0.621–0.727)
Largest	0.656 (0.611–0.717)
Smallest	***
Top 20 features largest metastasis 0.700 + cc (n = 289)
Unweighted average	0.671 (0.616–0.717)
Weighted average	0.656 (0.602–0.718)
Weighted average of largest 3	0.679 (0.623–0.733)
Largest + number of metastases	0.675 (0.614–0.715)
Largest	0.666 (0.615–0.714)
Smallest	***

***Collinear.