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. 2021 May 7;11:9755. doi: 10.1038/s41598-021-87844-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fundus images and optic disc OCT images in typical cases. (A–C) showed the fundus and optic disc structure images of a patient with high IOP (group A, IOP = 39.9 mmHg), a patient with moderate IOP (group B, IOP = 24.3 mmHg) and a normal subject (Group C, IOP = 14.3 mmHg). It can be seen that the higher the IOP level, the more serious the defect of optic nerve channel around the optic disc, the higher the C / D ratio, the deeper the CD and LCD on the OCT image, In addition, the curvature of lamina cribrosa increases only for the rough observation on the image. (long yellow line: BMO line on both sides; yellow curve: front surface of sieve plate; dark blue line: CD; light blue line: LCD; red line: PTT).