Table 2.
Comparison of baseline parameters of study participants with IOP ≥ 30 mmHg (Group A), 21 mmHg ≤ IOP < 30 mmHg (Group B), and normal IOP (Group C).
| Group A | Group B | Group C | P ValueA-B | P ValueA-C | P ValueB-C | |
|---|---|---|---|---|---|---|
| No. of eyes | 30 | 33 | 28 | |||
| Age (years) | 45.2 ± 18.2 | 41.1 ± 13.1 | 48.1 ± 14.9 | 0.300 | 0.509 | 0.504 |
| Male sex (%) | 66.7 | 72.7 | 53.6 | 0.608 | 0.317 | 0.125 |
| OD (%) | 53.3 | 42.4 | 46.4 | 0.395 | 0.607 | 0.759 |
| BCVA | 0.2 ± 0.2 | 0.5 ± 0.4 | 0.6 ± 0.3 | 0.004 | < 0.001 | 0.190 |
| Axial length (mm) | 24.5 ± 2.1 | 23.9 ± 3.1 | 24.7 ± 2.6 | 0.359 | 0.792 | 0.300 |
| VF MD (dB) | − 21.3 ± 7.6 | − 15.6 ± 7.8 | − 5.4 ± 5.5 | 0.008 | < 0.001 | < 0.001 |
| CCT (μm) | 502.3 ± 38.4 | 500.7 ± 33.9 | 496.8 ± 26.0 | 0.865 | 0.541 | 0.630 |
| Instant IOP (mmHg) | 29.2 ± 11.1 | 20.7 ± 9.7 | 17.4 ± 5.7 | 0.002 | < 0.001 | 0.121 |
| Maximum IOP (mmHg) | 44.0 ± 8.4 | 29.3 ± 8.0 | 20.8 ± 5.4 | < 0.001 | < 0.001 | < 0.001 |
| Mean CDR | 0.8 ± 0.1 | 0.7 ± 0.2 | 0.6 ± 0.2 | 0.446 | < 0.001 | 0.013 |
| Mean scan surface CDR | 0.8 ± 0.1 | 0.7 ± 0.2 | 0.6 ± 0.2 | 0.257 | < 0.001 | 0.004 |
| CV (mm3) | 0.8 ± 0.3 | 0.6 ± 0.4 | 0.4 ± 0.3 | 0.008 | < 0.001 | 0.066 |
| Mean RNFL thickness (mm) | 42.8 ± 12.7 | 69.2 ± 19.9 | 80.6 ± 29.2 | < 0.001 | < 0.001 | 0.075 |
| BMO (μm) | 1722.3 ± 213.8 | 1736.5 ± 408.9 | 1733.3 ± 203.1 | 0.865 | 0.841 | 0.970 |
| Cup depth (μm) | 547.8 ± 202.6 | 342.8 ± 221.5 | 161.6 ± 166.0 | < 0.001 | < 0.001 | < 0.001 |
| LCD (μm) | 655.3 ± 173.9 | 513.9 ± 154.8 | 404.5 ± 102.9 | 0.001 | < 0.001 | 0.002 |
| PLCSD (μm) | 876.8 ± 160.4 | 739.7 ± 152.1 | 648.2 ± 124.4 | < 0.001 | < 0.001 | 0.014 |
| PTT (μm) | 107.5 ± 42.6 | 171.1 ± 131.2 | 242.9 ± 142.3 | 0.014 | < 0.001 | 0.045 |
| LCT (μm) | 221.4 ± 69.8 | 225.8 ± 46.6 | 243.7 ± 47.3 | 0.770 | 0.163 | 0.142 |
| LCCI (μm) | 76.2 ± 28.0 | 58.0 ± 33.8 | 35.8 ± 29.2 | 0.024 | < 0.001 | 0.009 |
| aLCCI (μm) | 6.7 ± 2.4 | 4.5 ± 2.0 | 3.4 ± 2.4 | < 0.001 | < 0.001 | 0.043 |
| BMO-MRW | 129.6 ± 38.0 | 154.6 ± 67.3 | 195.1 ± 99.6 | 0.078 | 0.001 | 0.064 |
aLCCI = adjusted lamina cribrosa curvature index; BCVA = best-corrected visual acuity; BMO = Bruch’s membrane opening; BMO-MRW = Bruch’s membrane opening minimum rim width; CCT = central corneal thickness; CDR = cup-disk ratio; CV = cup volume; IOP = intraocular pressure; LCCI = lamina cribrosa curvature index; LCD = lamina cribrosa depth; LCT = lamina cribrosa thickness; MD = mean deviation; PLCSD = posterior lamina cribrosa surface depth; PTT = prelaminar tissue thickness; RNFL = retinal nerve fiber layer; VF = visual field.
All values < 0.05 at t-test are presented in boldface.