Table 3.
Linear regression relationship between IOP and factors.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| β | P value | β | P value | |
| Age (years) | − 0.034 | 0.747 | ||
| Gender (male/female) | − 0.048 | 0.651 | ||
| Eye (OD/OS) | 0.016 | 0.879 | ||
| BCVA | − 0.482 | < 0.001 | − 0.340 | 0.168 |
| Axial length (mm) | − 0.029 | 0.793 | ||
| VF MD (dB) | − 0.589 | < 0.001 | − 0.483 | < 0.001 |
| CCT (μm) | 0.103 | 0.344 | ||
| Mean CDR | 0.237 | 0.024 | − 0.062 | 0.615 |
| Mean scan surface CDR | 0.290 | 0.005 | 0.105 | 0.320 |
| CV (mmy) | 0.402 | < 0.001 | 0.286 | 0.162 |
| Mean RNFL thickness (mm) | − 0.633 | < 0.001 | − 0.237 | 0.006 |
| BMO (μm) | − 0.007 | 0.947 | ||
| Cup depth (μm) | 0.552 | < 0.001 | 0.562 | 0.001 |
| LCD (μm) | 0.515 | < 0.001 | 0.471 | 0.022 |
| PLCSD (μm) | 0.500 | < 0.001 | 0.504 | 0.013 |
| PTT (μm) | − 0.375 | < 0.001 | − 0.438 | 0.036 |
| LCT (μm) | − 0.096 | 0.363 | ||
| LCCI (μm) | 0.490 | < 0.001 | 0.595 | 0.014 |
| aLCCI (μm) | 0.541 | < 0.001 | 0.780 | 0.002 |
| Mean BMO-MRW (μm) | − 0.340 | 0.001 | − 0.483 | 0.004 |
aLCCI = adjusted lamina cribrosa curvature index; BCVA = best-corrected visual acuity; BMO = Bruch’s membrane opening; BMO-MRW = Bruch’s membrane opening minimum rim width; CCT = central corneal thickness; CDR = cup-disk ratio; CV = cup volume; IOP = intraocular pressure; LCCI = lamina cribrosa curvature index; LCD = lamina cribrosa depth; LCT = lamina cribrosa thickness; MD = mean deviation; PLCSD = posterior lamina cribrosa surface depth; PTT = prelaminar tissue thickness; RNFL = retinal nerve fiber layer; VF = visual field.
Statistical analysis was performed using the general linear model. Statistically significant values are shown in boldface. Factors with P < 0.1 in the univariate analysis were included from the multivariate analysis. All values < 0.05 at univariate and multivariate analysis are presented in boldface.