Table 1.

Protein-based biomimetic materials and current application status.

Materials	Applications	Cell types and animals	Research approaches	Ref.
Phospholipids and membrane proteins from leukocytes	Treatment and Diagnosis	Murine 4T1 cells; male apolipoprotein E (ApoE) –/– mice; Female BALB/c mice	In vivo	[14]
GST	Tumor imaging	E. coli BL21 (DE3) cells; Hela cells; C57BL\6 mice; female Balb/c mice	In vivo and in vitro	[15]
BSA	Diagnosis	MCF-7 cells	In vivo and in vitro	[8]
BSA	Diagnosis	MGC803 gastric cells	In vitro	[17]
rHDL	Treatment	HepG2 cells; MCF-7 cells; Female BALB/c nude mice	In vivo and in vitro	[18]
Albumin	Treatment	U87 cells; C6, GL216, and U251 cells; Luc-U87 cells; U87 orthotopic glioma mice;	In vivo and in vitro	[19]
GroEL	Treatment	MDA-MB-231; Panc-1; HPNE and 293T; BALB/c nude mice	In vivo and in vitro	[22]
Silk protein	Drug delivery	Human skin fibroblast (ATCC CRL-2522) and colorectal adenocarcinoma (Caco-2; ATCC HTB-37) cells	In vitro	[72]
AXT050	Drug delivery	MDA-MB-231 cells and microvascular endothelial cell (MEC) cells	In vivo and in vitro	[73]