Table 1.
Characteristics of Men Aged 18 to 55 Years Presenting With Incident MI, Categorized by Time
| Characteristic | 1987-1995 (N=145) | 1996-2004 (N=195) | 2005-2012 (N=188) | Ptrend |
|---|---|---|---|---|
| Age at MI (y), mean ± SD | 47.3±6.2 | 47.3±6.1 | 47.5±6.7 | .771 |
| Risk factors | ||||
| Current smoker, no. (%) | 77 (53.5) | 100 (51.3) | 85 (45.2) | .126 |
| Body mass index (kg/m2), mean ± SD | 29.3±6.8 | 30.4±5.8 | 30.4±6.0 | .116 |
| Familial coronary heart disease, no. (%) | 50 (36.5) | 60 (30.8) | 57 (30.5) | .277 |
| Hypertension, no. (%) | 53 (36.6) | 70 (35.9) | 88 (46.8) | .045 |
| Hyperlipidemia, no. (%) | 37 (25.5) | 84 (43.1) | 109 (58.0) | <.001 |
| Diabetes mellitus, no. (%) | 12 (8.3) | 22 (11.3) | 31 (16.5) | .022 |
| Charlson Comorbidity Index score, no. (%) | .036 | |||
| 0 | 106 (73.1) | 145 (74.4) | 123 (65.4) | |
| 1-2 | 32 (22.1) | 39 (20.0) | 45 (23.9) | |
| ≥3 | 7 (4.8) | 11 (5.6) | 20 (10.6) | |
| MI characteristics, no. (%) | ||||
| Cardiac pain | 142 (97.9) | 190 (97.4) | 183 (97.3) | .738 |
| Killip class II-IV | 37 (26.1) | 34 (17.7) | 23 (12.2) | .001 |
| ST-segment elevation | 62 (43.1) | 84 (44.2) | 83 (44.1) | .850 |
| Presence of Q waves | 62 (44.0) | 116 (64.4) | 108 (61.0) | .004 |
| GRACE score, mean ± SD | 75.6±18.7 | 74.0±15.6 | 71.9±18.3 | .057 |
| MI management, no. (%) | ||||
| Reperfusion or revascularization during hospitalization | 113 (78.5) | 158 (81.0) | 166 (88.3) | .016 |
| Aspirin at discharge | 120 (84.5) | 184 (95.3) | 180 (96.8) | <.001 |
| β-blockers at discharge | 99 (69.7) | 173 (89.6) | 178 (95.7) | <.001 |
| Statins at discharge | 5 (3.5) | 122 (63.2) | 180 (96.8) | <.001 |
| Attended ≥1 cardiac rehabiliation session | 120 (85.1) | 157 (81.8) | 136 (73.1) | .006 |
GRACE, Global Registry of Acute Coronary Events; MI, myocardial infarction.