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. 2021 Apr 8;5(2):423–430. doi: 10.1016/j.mayocpiqo.2021.01.012

Table 1.

Univariate and Multivariate Analysis Between Progressive Lymphoma and Sepsis Groupa,b

Parameters Progressive Lymphoma (n=18) Sepsis Only (n=33) P (univariate) P (multivariate)
Hospitalization
 Age at time of hospitalization (y), median (IQR) 63 (48-78) 68 (60-80) .23 .8
 Male, no. (%) 13 (72) 20 (61) .54 .58
 Non-Hodgkin lymphoma, no. (%) 18 (100) 32 (97) .28
 Aggressive non-Hodgkin lymphoma, no. (%) 18 (100) 29 (88) 0.54
 Previous lines of treatment, median (IQR) 2 (1-4) 2 (1-3) .23
 Hemoglobin (g/dL), median (IQR) 10.3 (9.5-11.2) 9.9 (8.1-11.6) .64 .52
 White blood cell count (109/L), median (IQR) 7.2 (5.6-18.8) 7.9 (3.5-17.9) .69 .66
 Platelets (109/L), median (IQR) 83 (38-192) 126 (98-223) .4 .72
 Creatinine (mg/dL), median (IQR) 0.96 (0.73-1.1) 1.2 (0.8-1.6) .09 .22
 Serum albumin (g/dL), median (IQR) 3.2 (2.9-3.9) 3.4 (2.8-3.9) .44 .38
 Lactate, initial (mmol/L; normal <2.2 mmol/L), median (IQR) 3.25 (2.9-5.0) 3.5 (2.9-4.4) .89 .49
 Peak lactate (mmol/L), median (IQR) 7.35 (5.1-15.2) 6.9 (5.4-8.1) .83
 LDH (U/L; normal <222 U/L), median (IQR) 665 (275-2980) 262 (217-373) .005c .003c
Before hospitalization
 Age (y) at time of lymphoma diagnosis, median (IQR) 62.5 (48-77) 68 (57-74) .42
  LDH (U/L) at time of lymphoma diagnosis, median (IQR) 318 (200-569) 309 (207-483.5) .85
a

IQR, interquartile range; LDH, lactate dehydrogenase.

b

SI conversion factors: To convert creatinine values to μmol/L, multiply by 88.4; to convert albumin values to g/L, multiply by 10.

c

Statistically significant.