Table 2.
Subgroup Analysis in Patients With or Without Heart Failure After Matchinga
Hyperkalemia |
Normokalemia |
Relative Risks |
||||
---|---|---|---|---|---|---|
No. of Events | % | No. of Events | % | Hazard Ratio | 95% CI | |
Overall | n=5859 | n=5859 | ||||
Death | 745 | 12.7 | 172 | 2.9 | 4.40 | 3.74-5.18 |
Hospitalization for cardiac eventsb | 278 | 4.7 | 140 | 2.4 | 1.95 | 1.59-2.39 |
Hospitalization for HF | 581 | 9.9 | 114 | 1.9 | 5.09 | 4.17-6.21 |
Renal replacement therapy introduction | 402 | 6.9 | 52 | 0.9 | 7.54 | 5.73-9.91 |
With HF | n=1548 | n=1575 | ||||
Death | 308 | 19.9 | 81 | 5.1 | 4.05 | 3.18-5.16 |
Hospitalization for cardiac eventsb | 141 | 9.1 | 68 | 4.3 | 2.11 | 1.58-2.81 |
Hospitalization for HF | 371 | 24.0 | 86 | 5.5 | 4.67 | 3.71-5.89 |
Renal replacement therapy introduction | 80 | 5.2 | 17 | 1.1 | 4.60 | 2.78-7.62 |
Without HF | n=4311 | n=4284 | ||||
Death | 437 | 10.1 | 91 | 2.1 | 4.81 | 3.83-6.03 |
Hospitalization for cardiac eventsb | 137 | 3.2 | 72 | 1.7 | 1.84 | 1.38-2.45 |
Hospitalization for HF | 210 | 4.9 | 28 | 0.7 | 7.17 | 4.84-10.62 |
Renal replacement therapy introduction | 322 | 7.5 | 35 | 0.8 | 8.93 | 6.38-12.51 |
HF = heart failure.
Cardiac event includes myocardial infarction, arrhythmia, and cardiac arrest.