Table 3.
Association of cardiovascular disease risk factors with frailty status in 458 Chinese older adults aged 65–94 years.
| Variable | Prefrail, |
Frail |
|||||
|---|---|---|---|---|---|---|---|
| Unadjusted OR (95% CI) | Age- and sex- adjusted OR (95% CI) | All-covariate-adjusted OR (95% CI) | Unadjusted OR (95% CI) | Age- and sex- adjusted OR (95% CI) | All-covariate-adjusted OR (95% CI) | ||
| Blood Pressure, mmHg | SBP<140 & DBP <90 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| SBP≥140 or DBP ≥90 | 1.03(0.68,1.56) | 0.98(0.64,1.50) | 0.94(0.59,1.50) | 0.43(0.19,0.96) | 0.39(0.16,0.92) | 0.31(0.11,0.87)a | |
| WC, cm | Male <85 or female <80 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| Male ≥85 or female ≥80 | 0.76(0.46,1.27) | 0.75(0.44,1.28) | 0.73(0.41,1.30) | 0.57(0.26,1.25) | 0.54(0.22,1.33) | 1.15(0.36,3.68) | |
| BMI, kg/m2 | 18.5–23.99 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| <18.5 | 1.09(0.26,4.54) | 1.13(0.26,4.87) | 0.57(0.11,2.85) | 2.15(0.33,13.88) | 3.17(0.43,23.51) | 1.01(0.11,9.73) | |
| 24–27.99 | 0.96(0.62,1.48) | 1.01(0.64,1.59) | 1.14(0.69,1.88) | 0.72(0.33,1.56) | 0.85(0.37,1.96) | 1.31(0.49,3.48) | |
| ≥28 | 1.94(0.97,3.88) | 2.00(0.98,4.08) | 2.26(1.05,4.84)b | 1.74(0.60,5.01) | 1.93(0.62,6.04) | 3.53(0.95,13.05) | |
| FG, mmol/L | <6.1 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| ≥6.1 | 1.22(0.75,1.20) | 1.19(0.71,1.97) | 1.14(0.63,2.05) | 1.93(0.90,4.13) | 1.91(0.83,4.37) | 2.66(0.96,7.41) | |
| TC, mmol/L | <6.2 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| ≥6.2 | 1.70(0.54,5.31) | 1.36(0.42,4.38) | 1.05(0.31,3.52) | 0.84(0.09,7.68) | 0.49(0.05,4.98) | 0.46(0.04,5.16) | |
| TG, mmol/L | <2.3 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| ≥2.3 | 0.71(0.45,1.11) | 0.70(0.44,1.11) | 0.66(0.40,1.08) | 0.91(0.43,1.95) | 0.91(0.40,2.06) | 0.79(0.31,2.02) | |
| LDL-C, mmol/L | 4.1 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| ≥4.1 | 1.53(0.70,3.36) | 1.54(0.69,3.47) | 1.77(0.76,4.13) | 1.54 (0.45,5.29) | 1.39(0.36,5.37) | 2.09(0.48,9.09) | |
| HDL-C, mmol/L | ≥1.0 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| <1.0 | 0.57(0.34,0.96) | 0.54(0.31,0.93) | 0.45(0.25,0.80)c | 1.26(0.57,2.79) | 1.05(0.44,2.53) | 0.99 (0.35,2.77) | |
Note: The covariates included age, sex, drinking, smoking, income, years of education, MMSE, GDS, MNA and IADL scores, antihypertensive medication use, antidiabetic medication use and cholesterol lowering medication use. aP=0.026; bP=0.036; cP=0.007. SBP = systolic blood pressure. DBP = diastolic blood pressure. WC = waist circumference. BMI = body mass index. FG = fasting glucose. TC = total cholesterol. TG = triglycerides. LDL-C = low-density lipoprotein cholesterol. HDL-C = high-density lipoprotein cholesterol. MMSE = Mini-Mental State Examination. GDS = Geriatric Depression Scale. MNA = Mini-nutrition Assessment. IADL = Instrumental Activities of Daily Living.