Figure 5.

Residual mitotic cDC1-like cells in Batf3−/− mice increase expression of cDC2 features

(A) GO analysis of cDC1 clusters C4, C6, C12, C17, and C18 (see Table S7).

(B) Distribution of cells assigned to WT and Batf3−/− genotypes.

(C) Trajectory analysis using RNA velocity.

(D) DEGs between WT and Batf3−/− of cDC1 cluster C6 (see Table S1).

(E) Top 40 DEGs between Batf3−/− mitotic cDC1 state C6 and Batf3−/− mitotic cDC2 state C5.

(F) Gene expression of canonical cDC2 and cDC1 features between mitotic cDC1 state C6 and mitotic cDC2 state C5 (related to Figure S5).

(G) Protein expression (adt) of canonical cDC2 and cDC1 features between mitotic cDC1 state C6 and mitotic cDC2 state C5. (H) DEGs between WT and Batf3−/− of cDC1 cluster C4 (see Table S1).

(I) Gene and protein expression of canonical cDC1 features between mitotic cDC1 (C6), immature cDC1 (C4), and mature cDC1 (C12).