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. 2021 Apr 16;24(5):102431. doi: 10.1016/j.isci.2021.102431

Figure 2.

Figure 2

Apoferritin ameliorated MPTP-induced loss of dopaminergic neurons in the SN

(A) The number of TH-positive neurons in the SNpc were significantly reduced after MPTP treatment. Apoferritin ameliorated the loss of TH-positive neurons caused by MPTP. The scale bar represents 200 μm (top) and 50 μm (below).

(B) Statistical analysis of TH-positive neurons as shown in (A).

(C) The expression of TH was reduced in the SN in MPTP-treated mice. Apoferritin suppressed MPTP-induced decrease in the expression of TH. Data were presented as percentage of control.

∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, compared with the control. #p < 0.05, ##p < 0.01, compared with the MPTP. Data were expressed as mean ± SEM (n = 8, 9 in each group).