Figure 5.

Qualitative type and orderings of transitions are preserved despite large animal-to-animal variability in critical temperatures and pH. (A) Each horizontal line represents one preparation exposed to a range of pH at 25°C (n = 5). The qualitative activity pattern, or state, is indicated with color: green corresponding to bursting, yellow to tonic spiking, and red to silence. (B) The same preparation was exposed to each condition and plotted in the same order across conditions (n = 8), meaning the first horizontal line in the temperature conditions corresponds to the first horizontal line in the pH conditions. (C) The top set of preparations were exposed to increasing temperature (n = 20, 13 from Figs. 2 and 7 additional without intracellular recordings), and the bottom set of preparations were exposed to decreasing pH (n = 15). (A–C) Preparations are ordered based on transition to silence. To see this figure in color, go online.