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Substitution of canonical H2A with H2A.B results in more open nucleosome structures (top). Sequence alignment of H2A and H2A.B histones (bottom) shows that H2A.B has a shorter docking domain (boxed), alterations to the acidic patch, and no C-terminal tails (5). Basic residues are in blue, acidic in red, hydrophobic in green, and polar in black. To see this figure in color, go online.
