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. 2021 May 6;218(7):e20201745. doi: 10.1084/jem.20201745

Figure 2.

Figure 2.

Liver histology and CD34 expression in humans and mice with GIMAP5 deficiency. (A) Photomicrographs of abnormal CD34 immunostaining in liver sinusoids of four unrelated patients (P1-1, P2-1, P3-1, and P4-1) as compared with an unaffected control. (B) Photomicrographs of abnormal CD34 sinusoidal expression is shown in the liver sections from C57BL/6 Gimap5sph/sph mice at 2, 3, and >7 wk old and in adult C57BL/6 Gimap5sph/sphRag1−/− mice as compared with Gimap5sph/+ control mice. Histological data from 2-wk-old, 3-wk-old, adult Gimap5sph/sph, and adult Gimap5sph/sphRag1−/− mice was verified at least four, two, seven, and three independent times, respectively. Littermates were used as controls. Scale bar = 50 µm.