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Relative intracellular concentration of THPE-NCs derived from IFI and PK modeling at 0.5, 1, 2 and 3 h of incubation with 2.67 (A), 8 (B), and 24 (C) μg/mL of THPE-NCs, respectively, as well as for an additional 1 and 2 h incubation after removing NCs from the culture media at 3 h. The value at 0.5 h is used as the reference.
