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The relationship between caveolin-1 levels and cytotoxicity with SMA-doxorubicin micelles with high loading (blue) and low loading (red) against MDA-MB-231 (high caveolin-1 levels) and DU-145 cells (low caveolin-1 levels), when they are endocytosed in caveolin-mediated pathways. Reprinted with the permission from Ref. 94. Copyright © 2014 Nehoff H et al.
