Table 5.
Epidemiological, clinical, and pathological features of patients with disease progression.
| Patient A | Patient B | Patient C | |
|---|---|---|---|
| Age at diagnosis, years | 51 | 36 | 33 |
| Gender | F | F | F |
| Thyroglobulin, μg/L | 10 | 21 | 2 |
| TgAb | Undetectable | Undetectable | Undetectable |
| Thyroid volume, mL | 10 | 10 | 15 |
| Maximum diameter at baseline, mm | 9 | 13 | 13 |
| Maximum diameter at last follow-up, mm | 8 | 18 | 18 |
| Nodule volume at baseline, mL | 0.22 | 1.1 | 0.8 |
| Nodule volume at last follow-up, mL | 0.26 | 2.1 | 1.6 |
| Nodule’s echography pattern | Hypoechoic, irregular margins | Hypoechoic, irregular margins, microcalcification | Hypoechoic, microcalcification |
| Thyroid subcapsular proximitya | Yes | yes | yes |
| Cytology | TIR4 | TIR4 | TIR4 |
| Follow-up under active surveillance, months | 12 | 13 | 23 |
| Surgery | Total thyroidectomy and lymphoadenectomy of laterocervical compartment | Total thyroidectomy | Total thyroidectomy |
| TMN (8° edition) | T1b(m)N1bM0 | T1bNXMX | T1bNXMX |
| Histological variant of PTC | Tall cell | Classic | Classic |
| Maximum diameter histology (mm) | 13 | 17 | 17 m |
| Remnant radioablation | Yes (activity 1100 MBq) | No | No |
| Follow-up after surgery, months | 36 | 12 | 6 |
| Outcome | Excellent response | Excellent response | Excellent response |
aThyroid capsular proximity is defined as a lesion located near the thyroid capsule, within 3 mm abutting the capsule.