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. 2021 Apr;9(7):590. doi: 10.21037/atm-20-7383

Figure 3.

Figure 3

Radiolabel scintigraphy to determine lungs dose and mass balance. (A) Dosing with radiolabeled aerosol; (B) Imagining of thorax post inhalation; (C) Device components on scanner with representative scan; (D) Representative radiolabel images; (E) mass balance across different compartments at 10, 30 and 50 L/Min. After the subject inhaling radiolabeled aerosol via HFNC at different gas flows (A), the subject sat close to the gamma camera detector (B) to scan the anterior upper airway/face (C), followed by a scan of device components (nebulizer, humidifier chamber, tubing, cannula, mask, and filter) (C). Representative scans at gas flows of 10, 30 and 50 L/min (D) and result of aerosol deposition in different compartments at 10, 30 and 50 L/min gas flows (E) were modified from (31).