Skip to main content
. 2021 Apr;9(7):577. doi: 10.21037/atm-20-7160

Table 1. Main components and mechanism of action of commercial hemostatic products.

Category Product Name Manufacturer Product type Main components Mechanism of action Ref.
Inorganic based hemostatic materials Wound Stat Unavailable Hemostatic granules Smectite Procoagulant, Mucoadhesive agent (10)
Combat Gauze Z-Medica Hemostatic gauze Kaolin Procoagulant (11)
Quickclot Z-Medica Hemostatic granules Zeolite Factor concentrators (12)
Polysaccharide based hemostatic materials Hemcon HemCon Medical Technologies Hemostatic bandage Chitosan Procoagulant (13)
Celox MedTrade Hemostatic granules Cchitosan Procoagulant (14)
TraumaStat OreMedix Hemostatic gauze Chitosan Procoagulant (15)
Arista,Hemostase Bard Hemostatic microspheres Starch Factor concentrators (16)
Surgicel Johnson & Johnson Hemostatic gauze Cellulose Procoagulant (17)
Traumastem Baxter Hemostatic gauze Cellulose Procoagulant (18)
Kaltostat ConvaTec Hemostatic film Alginate Mucoadhesive agent (19)
Sorbalgon Harmann
Biologically derived homeostatic materials Recothrom ZymoGenetics Hemostatic solution Thrombin Procoagulant (20)
Thrombin-JMI King Pharmaceuticals Hemostatic powder Thrombin Procoagulant (21)
Evithrom Johnson & Johnson Hemostatic solution Thrombin Procoagulant (22)
Tisseel Evicel Baxter Ethicon Sealant Fibrin Procoagulant (23)
Vitagel Stryker Sealant Fibrin Procoagulant
Evarrest Omrix Biopharmaceuticals Hemostatic patch Fibrin Procoagulant
ARTISS Baxter Sealant Fibrin Procoagulant (24)
Stypro Curasan Hemostatic sponge Collagen Factor concentrators, Procoagulant (25)
HEMOBLAST Biom’Up Hemostatic powder Collagen Procoagulant (26)
Floseal Baxter Hemostatic matrix Gelatin Procoagulant (21)
Surgiflo Johnson & Johnson Hemostatic matrix Gelatin Procoagulant (17)
Gelfoam Pfizer Hemostatic sponge Gelatin Factor concentrators (27)
Lyostypt Aesculap Hemostatic Microfibrillar Microfibrillar Collagen Procoagulant (28)
Endo-Avitene Bard Hemostatic Microfibrillar Microfibrillar Collagen Procoagulant (27)
Costasis Cohesion Technologies Hemostatic Spray Microfibrillar Collagen Procoagulant (29)
Bioglue CryoLife Tissue adhesive Bovine albumin Mucoadhesive agent (30)
PreveLeak Baxter Tissue adhesive Bovine albumin Mucoadhesive agent (31)
Synthetically derived hemostatic materials CoSeal
DuraSeal
Baxter
Coviden
Sealant Polyethylene glycol Mucoadhesive agent (22)
Dermabond Johnson & Johnson Tissue adhesive Cyanoacrylate Mucoadhesive agent (32)
Histoacryl B. Braun Melsungen AG