Table 1.
Demographic characteristics
| IoAPS (n = 44) |
ItAPS (n = 39) |
tAPS+oAPS (n = 9) |
P value All groups |
P value IoAPS vs. ItAPS |
|
|---|---|---|---|---|---|
| Age (years), mean ± SD | 33.16 ± 4.22 | 41.92 ± 11.97 | 35.22 ± 3.82 | 0.000 | 0.000 |
| BMI (kg/m2), mean ± SD | 22.84 ± 3.21 | 24.60 ± 4.20 | 24.61 ± 2.69 | 0.086 | 0.024 |
| Duration, months median (Q1, Q3) | 48.50 (36.00, 77.00) | 51.00 (22.00, 93.00) | 41.00 (15.00, 61.00) | 0.657 | 0.404 |
| Smoking history, n (%) | 1 (2.27) | 1 (2.56) | 0 | 1.000 | 1.000 |
| Cardiovascular risk factors, n (%) | 3 (6.82) | 16 (41.03) | 3 (33.33) | 0.002 | 0.000 |
| Coronary heart disease | 0 (0) | 3 (7.69) | 0 | 0.219 | 0.099 |
| Hypertension | 1 (2.27) | 6 (15.38) | 2 (22.22) | 0.028 | 0.048 |
| Obesity (BMI > 30 kg/m2) | 2 (4.55) | 8 (20.51) | 0 | 0.048 | 0.040 |
| Diabetes mellitus | 0 (0) | 0 (0) | 0 | – | – |
| Hyperlipidemia | 0 (0) | 3 (7.69) | 1 (11.11) | 0.107 | 0.099 |
| Complications, n (%) | 12 (27.27) | 20 (51.28) | 4 (44.44) | 0.079 | 0.041 |
| Kidney disease | 2 (4.55) | 3 (7.69) | 0 | 0.799 | 0.662 |
| Thrombocytopenia | 9 (20.45) | 17 (43.59) | 4 (44.44) | 0.056 | 0.033 |
| Non-stroke CNS manifestations | 1 (2.27) | 3 (7.69) | 0 | 0.573 | 0.337 |
| Valvular heart disease | 4 (9.09) | 3 (7.69) | 1 (11.11) | 1.000 | 1.000 |
| aGAPSS median (Q1, Q3) | 4 (4, 12) | 10 (4, 13) | 13 (6, 15) | 0.001 | 0.001 |
BMI, body mass index; cardiovascular risk factors and complications positive, patients with at least one positive subgroup symptom; CNS, central nervous system; aGAPSS, adjusted Global Anti-Phospholipid Syndrome Score