Table 4.

Univariate and multivariate Cox regression of predictors of recurrent thromboses in patients with APS

Variables	Univariate regression			Multivariate regression
	HR	95% CI	P value	HR	95% CI	P value
ItAPS phenotype	17.115	2.237–130.927	0.006	15.791	1.747–142.763	0.014
Age (per 10 years)	0.857	0.417–1.762	0.674
High homocysteine levela	1.013	0.223–4.597	0.987
Cardiovascular risk	3.316	1.140–9.646	0.028
Triple positive antibodies	1.433	0.494–4.155	0.508
Single anti-β2GPI positive	0.382	0.084–1.730	0.212
Thrombocytopenia	2.030	0.079–5.814	0.187

^aHigh homocysteine level is defined as homocysteine > 15 μmol/L

HR, hazard ratio; CI, confidence interval