Figure 4.

TGFBI enhanced the G²/M phase arrest induced by paclitaxel in MDA-MB-231 cells. (A) Western blot analysis of TGFBI expression in MDA-MB-231 cell 48hours after transfection of TGFBI vector or empty vector; (B) measurements of the cell cycle distribution of MDA-MB-231 cells after transfection with TGFBI or empty vector for 48 hours and treatment with 12.5 µM paclitaxel for 24 hours. *, P<0.05; (C) representative images of flow cytometry for untreated cells and those treated with paclitaxel after transfection with TGFBI or empty vector.