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. 2021 Apr;9(8):659. doi: 10.21037/atm-21-935

Figure 3.

Figure 3

The CK1-mediated cell proliferation and metastasis closely correlates with the expression of AKT, p-AKT (Thr-308), and MMP2. (A) Immunoblot analysis demonstrated that the levels of STAT3and JAK2 protein expression were not affected by CK1 expression. (B) Western blot analysis demonstrated that the protein expression of AKT, p-AKT, and MMP2 were significantly affected by variations in CK1 expression. The gray value statistics table is shown below. * indicates a significant difference (P<0.05). (C) Representative images of AKT, p-AKT, and MMP2 staining by immunochemistry in tissues from patients (200×). The red arrow indicates a significant difference (P<0.05).