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. 2021 Apr;9(8):675. doi: 10.21037/atm-21-997

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Circular RNA hsa_circ_0097009 (circ0097009) is upregulated in hepatocellular carcinoma (HCC) cell lines and tissues. (A) Expression level of circ0097009 in normal and HCC cell lines. (B) Expression level of circ0097009 in HCC tissues and matched normal tissues. (C) RNase R digestion experiment was performed to confirm the circular structure of circ0097009. (D) Stability of the circular transcript circ0097009 and linear transcript SLC5A8 in 97H cells, as assessed by actinomycin D assays. **P<0.01.