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. 2021 Apr;9(8):684. doi: 10.21037/atm-21-1070

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Effect of SNO on the expression of the PPARγ protein and mRNA in L02 hepatocytes. (A,B) The expression levels of the PPARγ protein and mRNA in L02 cells; (C,D) the expression levels of targeting gene of SNO-PPARγ protein and mRNA in L02 cells; (E,F) the expression levels of the target of the PPARγ protein and mRNA in L02 cells. Experimental vs. NC group, *P<0.05. NC, negative control; NAFL, non-alcoholic fatty liver; NASH, non-alcoholic steatohepatitis; GSNO, SNO enhancer S-Nitrosoglutathione; PPARγ, peroxisome proliferators-activated receptors γ; SNO, S-nitrosylation; ap2, adapter protein2.