Table 1.

Identified exosomal cargoes of stem cells that improve ischemic diseases

Exosomes from Stem cells	Cargo	Disease
Cardiosphere-derived cells	miRNA-210, miRNA-130a, miRNA-126 miRNA-146a	Myocardial ischemia
CD34+ cell	Hedgehog proteins	Myocardial ischemia
Embryonic Stem Cells	Not known	Myocardial ischemia
Induced Pluripotent Stem Cells	Not known	Myocardial ischemia
Mesenchymal Stem Cells	CXCR4, miRNA-21, EMMPRIN	Myocardial ischemia
Stem cells derived from adipose tissue	miRNA-125a	Chronic wound healing
Mesenchymal Stem Cells	miRNA-21-3p, miRNA-126, VEGF	Chronic wound healing
CD34 +	miRNA-126-3p	Chronic wound healing
Stem cells derived from adipose tissue	IL-6	Chronic wound healing
Stem cells derived from adipose tissue	miRNA-181b-5p	Stroke
Mesenchymal Stem Cells	Not known	Stroke
Mesenchymal Stem Cells	VEGF protein, miRNA-210-3p,	Peripheral arterial disease
CD34 + cells	miRNA-126-3p	Peripheral arterial disease