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. 2021 May 7;21:252. doi: 10.1186/s12935-021-01930-y

Fig. 4.

Fig. 4

Association of HHLA2 expression in ovarian cancer cells and CD8+ TIL status. The HHLA2 positive cells and CD8 positive cells were stained by IHC. a HHLA2 positive and c HHLA2 negative staining on ovarian cancer cells. b, d CD8 staining on ovarian cancer tissue slides. The red arrowhead indicated CD8+T cells. Magnification: × 200. A, B and C, D were from the same tumour tissue respectively. e The average CD8+ TIL number was compared between patients with negative HHLA2 expression and positive HHLA2 expression