Table 3.

Multivariate Cox Regression Analysis of PFS and OS

Variable	PFS			OS
	HR	95% CI	P value	HR	95% CI	P value
Age ≥ 65 (vs Age < 65 years old)	0.986	0.564–1.722	0.960	1.560	0.846–2.877	0.154
Tobacco use (vs none)	1.174	0.680–2.027	0.565	1.745	0.946–3.218	0.075
No. of previous treatment lines > 3 (vs ≤ 3)	1.523	0.870–2.669	0.141	0.890	0.486–1.629	0.706
ANC	1.095	1.030–1.163	0.003*	1.057	1.003–1.113	0.037*

Notes: Cox proportional hazard models using PFS and OS as a timescale to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). *p<0.05.