Table 4.

ORR, PFS and OS According to Median ANC

ANC	N for CR+PR	Percentage (%)	P value
< 4.58	9	26.5
≥ 4.58	3	8.1	0.057
ANC	mPFS	95% CI	P value
< 4.58	7	4.4–9.6
≥ 4.58	5	4.4–5.7	0.024*
ANC	mOS	95% CI	P value
< 4.58	17.6	12.3–22.9
≥ 4.58	7.3	4.7–10.0	< 0.001*

Notes: The response to anlotinib between different groups were compared by Pearson χ2. The Log rank test was used for univariate analyses of PFS and OS. * p<0.05.