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. 2021 May 4;15:1903–1914. doi: 10.2147/DDDT.S305033

Table 3.

Effects of Silymarin on Organ Index of Liver, Lung and Kidney in Mice Induced by D-Gal/LPS (N=10/Group)

Groups Liver Index Lung Index Kidney Index
Normal 42.15±1.5aA 5.34±0.18b 13.96±0.55b
Model 34.10±2.63c 4.43±0.28c 11.26±0.49d
Silymarin-L 36.76±0.87c 5.32±0.17b 12.52±0.29c
Silymarin-H 38.78±1.3b 6.08±0.26a 14.84±1.07a

Notes: Model, treated with D-Gal/LPS (250 mg/kg·bw and 25 mg/kg·bw) injection; silymarin-L: treated with silymarin (75 mg/kg·bw) oral administration; silymarin-H: treated with silymarin (150 mg/kg·bw) oral administration. a–dThere was significant difference in different letters in the same column (P < 0.05), which was determined by Duncan’s multiple range test. AValues presented are the mean±standard deviation (SD) of different organ coefficients. Organ index (mg/g) = organ weight (mg)/body weight (g).