Table 3.
NO and H2S levels based on biomarkers and disease severity.
| NO Levels (nM) |
p-Value | H2S Levels (μM) |
p-Value | |||
|---|---|---|---|---|---|---|
| Mean (n) | ±SD | Mean (n) | ±SD | |||
| Troponin | 0.14 | 0.64 | ||||
| Troponin ≤0.04 ng/ml | 273.87(30) | 137.36 | 1.17 (31) | 0.21 | ||
| Troponin >0.04 ng/ml | 347.54 (13) | 176.18 | 1.14 (15) | 0.25 | ||
| D-Dimer | 0.08 | 0.85 | ||||
| D-Dimer ≤1000 ng/ml | 240.00 (14) | 111.99 | 1.14 (15) | 0.15 | ||
| D-Dimer >1000 ng/ml | 326.45 (31) | 163.98 | 1.13 (36) | 0.24 | ||
| Ferritin | 0.43 | 0.94 | ||||
| Ferritin ≤600 ng/ml | 266.12 (17) | 141.11 | 1.14(18) | 0.13 | ||
| Ferritin >600 ng/ml | 300.94 (35) | 153.24 | 1.14(40) | 0.23 | ||
| CRP | 0.56 | 0.76 | ||||
| CRP ≤ 1.8 mg/dl | 325.33 (9) | 138.17 | 1.15 (9) | 0.21 | ||
| CRP > 1.8 mg/dl | 294.62 (37) | 141.57 | 1.18 (43) | 0.21 | ||
| LDH | 0.004 | 0.22 | ||||
| LDH ≤ 260 U/L | 210.50 (10) | 64.41 | 1.08 (11) | 0.17 | ||
| LDH > 260 U/L | 323.16 (31) | 167.63 | 1.17 (35) | 0.22 | ||
| BNP | 0.21 | 0.11 | ||||
| BNP ≤ 1000 pg/ml | 255.00 (15) | 131.61 | 1.09 (16) | 0.12 | ||
| BNP > 1000 pg/ml | 322.53 (17) | 163.45 | 1.19 (20) | 0.21 | ||
| RDW | 0.16 | 0.92 | ||||
| RDW ≤ 14.5% | 265.86 (36) | 109.38 | 1.14 (37) | 0.23 | ||
| RDW > 14.5% | 323.17 (24) | 174.51 | 1.15 (30) | 0.18 | ||
| Lactate | 0.05 | 0.10 | ||||
| Lactate ≤ 1.25 mmol/L | 235.65 (17) | 64.79 | 1.08 (17) | 0.22 | ||
| Lactate> 1.25 mmol/L | 311.26 (27) | 177.96 | 1.19 (31) | 0.21 | ||
| Procalcitonin | 0.05 | 0.14 | ||||
| Procalcitonin ≤0.5 ng/ml | 251.34 (29) | 102.73 | 1.12 (31) | 0.23 | ||
| Procalcitonin >0.5 ng/ml | 334.70 (20) | 163.57 | 1.21 (23) | 0.19 | ||
| Severity of COVID | 0.29 | 0.009 | ||||
| Mild - Moderate | 274.02 (46) | 133.67 | 1.10 (46) | 0.17 | ||
| Severe | 314.68 (22) | 154.25 | 1.23 (22) | 0.24 | ||
| Outcome | <0.001 | 0.013 | ||||
| Alive | 263.65 (60) | 124.34 | 1.11 (60) | 0.17 | ||
| Expired | 464.43 (8) | 137.41 | 1.40 (8) | 0.25 | ||
CRP - C-Reactive Protein; LDH - Lactate Dehydrogenase; BNP - Brain Natriuretic Peptide; RDW - Red cell Distribution Width.