Table 1.
Number of autosomal genes showing LATE in samples studied by two independent RNA sequencing methods
| Cell type | Results from RNAseq analysis* | Results from scRNAseq analysis* | ||
|---|---|---|---|---|
| N. of expressed genes in samples without LOY | N. of LATE genes in samples with LOY | N. of expressed genes in normal non-LOY cells | N. of LATE genes in single cells with LOY | |
| NK cells | 9974 | 298 | 3021 | 37 |
| Monocytes | 9891 | 80 | 3634 | 28 |
| Granulocytes | 7497 | 57 | – | – |
| T lymphocytes | – | – | 2798 | 13 |
| B lymphocytes | – | – | 3112 | 3 |
| LCL’s | 9549 | 757 | – | – |
| Number of genes# | 11,472 | 1155 | 4631 | 75 |
| Number of LATE genes in vivo# | 420 | 75 | ||
Number of autosomal LATE genes detected in vivo by RNAseq and/or scRNAseq# = 489
*Results from RNAseq and scRNAseq analyses are shown separately for each cell type. The detected number (N.) of expressed genes as well as the number of LATE genes detected in different cell types using FDR < 0.1 are shown
#The number of unique genes after exclusion of overlaps between cell types and/or methods