Table 3.
Toxicity summary for treatment-related toxicities*
Event | All Grades N (%) | Grades 3-4 N (%) | |
---|---|---|---|
Cardiac | Cardiac disorders - other, specify | 10 (26) | 1 (3) |
Prolonged QTc | 20 (5) | 5 (13) | |
Gastrointestinal | Anorexia | 12 (32) | 0 (0) |
Diarrhea | 15 (39) | 3 (8) | |
Nausea | 26 (68) | 1 (3) | |
Vomiting | 18 (47) | 0 (0) | |
General | Fatigue/malaise | 23 (61) | 3 (8) |
Infusion-related reaction | 9 (24) | 0 (0) | |
Hematologic | Platelet count decreased | 9 (24) | 9 (24) |
White blood cell decreased | 11 (29) | 9 (24) | |
Laboratory | Increased AST/ALT | 9 (24) | 2 (5) |
Alkaline phosphatase increased | 13 (34) | 1 (3) | |
Neurologic | Dysgeusia | 12 (32) | 0 (0) |
Paresthesia | 10 (26) | 0 (0) | |
Peripheral sensory neuropathy | 11 (29) | 2 (5) |
Includes toxicities with incidence greater than 20%