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. 2020 Dec 7;2020(12):CD003864. doi: 10.1002/14651858.CD003864.pub3

Cabov 2010.

Methods Prospective double‐blind, placebo‐RCT
Participants 60 non‐edentulous patients consecutively admitted to the surgical ICU and requiring minimum stay of 3 days
Inclusion criteria: aged > 18 years, medical condition suggesting hospitalisation in the ICU for ≥ 3 days, and an eventual requirement for mechanical ventilation by oro‐ or nasotracheal intubation
Exclusion criteria: not reported
Interventions
  • Chlorohexidine: antiseptic decontamination of dental plaque and the oral mucosa with chlorhexidine gel

  • Placebo: placebo gel

Outcomes Outcomes: dental status assessed using a caries‐absent‐occluded score, and the amount of plaque assessed using a semi‐quantitative score
Samples of dental plaque, oral mucosa, and nasal and tracheal aspirates were collected for bacterial culture, and nosocomial infections were assessed
Notes Unclear whether any stroke‐specific data are available – e‐mail sent to study authors requesting further information