Table 1:
Demographics and preoperative anatomy
| Study cohort (N = 413) | TGA-IVS (N = 258) | TGA-VSD (N = 117) | TBA (N = 38) | P-value | |
|---|---|---|---|---|---|
| Male, n (%) | 280 (67.8) | 184 (71.3) | 72 (61.5) | 24 (63.2) | 0.133 |
| Age follow-up (years)a | 15.6 (0.1–41.1) | 15.7 (0.1–40.1) | 15.8 (0.2–41.1) | 12.3 (0.1–36.3) | 0.661 |
| Age follow-up (years)b | 15.6 (0.1–45.8) | 15.7 (0.1–40.6) | 15.8 (0.2–45.8) | 12.4 (0.1–36.9) | 0.706 |
| Coexisting findings, n (%) | |||||
| Arch abnormality | 35 (8.5) | 3 (1.2) | 14 (12.0) | 18 (47.4) | 5.5*10−16 |
| Bicuspid pulmonary valve | 27 (6.5) | 16 (6.2) | 10 (8.5) | 1 (2.6) | 0.337 |
| LVOTO | 16 (3.9) | 1 (0.4) | 10 (8.5) | 5 (13.2) | 3.0*10−6 |
| Coronary anatomy,cn (%) | |||||
| Usual (1LCx-2R, 1L-2CxR, 1L-2R-noCx) | 341 (82.6) | 224 (86.8) | 94 (80.3) | 23 (60.5) | 3.1*10−4 |
| Other | 67 (16.4) | 31 (12.0) | 21 (17.9) | 15 (3.9) | |
| Unknown | 5 (1.2) | 3 (1.2) | 2 (1.7) | 0 (0) | |
| Intramural course of LAD | 12 (2.9) | 8 (3.1) | 4 (3.4) | 0 (0) | 0.812 |
| Preoperative procedures, n (%) | |||||
| Balloon atrial septostomy | 216 (52.3) | 151 (58.5) | 57 (48.7) | 8 (21.1) | 4.0*10−5 |
| Previous PAB | 30 (7.2) | 11 (4.3) | 15 (12.8) | 4 (10.5) | 0.007 |
| Arterial switch operation | |||||
| One stage, n (%) | 371 (89.8) | 246 (95.3) | 94 (80.3) | 31 (81.6) | 1.0*10−5 |
| Median age | 8 days | 7 days | 11 days | 23 days | 9.2*10−13 |
| (0 day–0.9 years) | (0 day–0.5 years) | (1 day–0.9 years) | (4 days–0.6 years) | ||
| Two stage, n (%) | 42 (10.2) | 12 (4.7) | 23 (19.7) | 7 (18.4) | 1.0*10−5 |
| Median age | 166 days | 107 days | 238 days | 286 days | 0.256 |
| (7 days–12.7 years) | (7 days–5.1 years) | (46 days–12.7 years) | (32 days–1.7 years) | ||
| Lecompte manoeuvre, n (%) | 376 (91.0) | 243 (94.2) | 108 (92.3) | 25 (65.8) | 2.1*10−7 |
a
Median age (range) post-ASO.
b
Median age (range) post-birth.
c
Coronary anatomy description according to the Leiden Convention.
P-values based on Fisher–Freeman–Halton exact test for frequencies and Kruskal–Wallis test for median values of continue data.
ASO: arterial switch operation; IVS: intact ventricular septum; L or LAD: left anterior descending coronary artery; LVOTO: left ventricular outflow tract obstruction; PAB: pulmonary artery banding; R: right coronary artery; TBA: Taussig-Bing anomaly; TGA: transposition of the great arteries; VSD: ventricular septal defect.