Table 3:

Univariable and multivariable Cox proportional hazard analysis for reoperation or catheter interventions

		Univariable			Multivariable*
Risk factors	Events/total	Hazard ratio	95% CI	P-value	Hazard ratio	95% CI	P-value
Morphological subtype				1.35*10−10			0.023
TGA-IVSa	46/258	1			1
TGA-VSD	41/117	2.30	1.51–3.51	1.06*10−4	1.84	1.18–2.89	0.008
TBA	24/38	5.33	3.25–8.76	3.91*10−11	1.92	0.95–3.91	0.071
Gender
Maleb	72/280	1			1
Female	39/133	1.19	0.80–1.75	0.39	1.18	0.79–1.77	0.41
Weight at ASO (per 1 kg)		1.10	1.04–1.17	4.49*10−4	1.03	0.95–1.12	0.41
LVOTO
Noc	106/397	1			1
Yes	5/16	1.13	0.54–3.23	0.55	1.01	0.39–2.62	0.99
Aortic arch repair
Nod	84/378	1			1
Yes	27/35	5.75	3.69–8.95	9.02*10−15	3.72	2.13–6.50	4.0*10−6
Lecompte
Noe	17/29	1			1
Yes	93/384	0.29	0.17–0.48	3.00*10−6	0.74	0.38–1.43	0.37
Prior PAB
Nof	99/383	1			1
Yes	12/30	2.00	1.10–3.65	0.023	1.24	0.59–2.61	0.57
Coronary artery anatomy
Usual (1LCx-2R, 1L-2CxR, 1L-2R, noCx)g	79/341	1			1
Other (non-usual)	31/67	2.65	1.74–4.02	5.00*10−6	1.92	1.20–3.07	0.007

Reference categories of covariate:

^amorphological subtype ‘TGA-IVS’,

^b‘male sex’,

^c‘no left ventricular outflow tract obstruction’,

^d‘no aortic arch repair associated with ASO’,

^e‘no Lecompte manoeuvre’,

^f‘no pulmonary artery banding prior to ASO’,

^g‘usual coronary artery anatomy’. *Variables included for MV analysis: morphological subtype, sex, weight, aortic arch repair, pulmonary artery banding prior to ASO and coronary artery anatomy.

ASO: arterial switch operation; CI: confidence interval; L: left coronary artery; LVOTO: left ventricular outflow tract obstruction; PAB: pulmonary artery banding; R: right coronary artery; TBA: Taussig-Bing anomaly; TGA: transposition of the great arteries; TGA-IVS: TGA with intact ventricular septum; TGA-VSD: TGA with ventricular septal defect.