TABLE 1.
A selection of instruments for accurate mass MS/MS analysis (2016) and their maximum mass resolving power and acquisition speed
# | Instrument | MS1 mass resolving power | MS/MS acquisition speed (spectra/s) |
---|---|---|---|
1 | Agilent 6550 iFunnel QTOF | 40 000 | 50 |
2 | Agilent 7200 GC/QTOF | 13 500 | 50 |
3 | Bruker GC-micrOTOF-Q II | 16 500 | 40 |
4 | Bruker impact II | 50 000 | 50 |
5 | JEOL SpiralTOF-TOF | 60 000 | 10 |
6 | Perkin Elmer AxION iQT GC/MS/MS | 12 000 | 50 |
7 | SCIEX TripleTOF 6600 | 35 000 | 100 |
8 | SCIEX TOF/TOF 5800 | 26 000 | 10 |
9 | SCIEX X500R | 35 000 | 100 |
10 | Shimadzu LCMS-IT-TOF | 10 000 | 10 |
11 | ThermoFisher Q Exactive HF | 240 000 | 18 |
12 | ThermoFisher Q Exactive GC Orbitrap GC-MS/MS | 140 000 | 12 |
13 | ThermoFisher Orbitrap Fusion Tribrid | 450 000 | 15 |
14 | Waters Synapt G2-Si HDMS | 60 000 | 30 |
15 | Waters Xevo G2-XS QToF | 40 000 | 30 |
Data were obtained from public sources and might vary slightly. Some instruments allow collecting data at different mass resolving power in MS1 and MS/MS in order to increase the sensitivity or duty cycle.