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. 2021 May 5;13:3629–3637. doi: 10.2147/CMAR.S281690

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© 2021 Li et al.

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AML group exhibited altered expression of circ_POLA2, mature miR-34a and miR-34a precursor. BM samples were collected from AML patients (n = 50) and healthy controls (n = 50), followed by RNA preparations and RT-qPCRs to analyze the expression of circ_POLA2 (A), mature miR-34a (B) and miR-34a precursor (C). Unpaired t test was used to compare two groups. The Kaplan-Meier survival curve showed the survival rate in patients with high expression levels of circ_POLA2 and those with low expression levels of circ_POLA2 (D). ***p < 0.001.