Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 25;12(10):1536–1548. doi: 10.1111/1759-7714.13937

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Gefitinib‐resistant persisters (GRPs) of PC9 and HCC827 show gene signatures reminiscent of epithelial‐mesenchymal transition (EMT) and cancer stem cells (CSCs). (a) The mRNA expression of E‐cadherin, fibronectin, vimentin, and N‐cadherin is evaluated by quantitative real‐time PCR (qPCR). (b) The mRNA expression of stem cell‐related factors is evaluated by qPCR. (c) The mRNA expression of zinc‐finger E‐box‐binding homeobox 1 (ZEB1) and BMI1, and miRNA expression of miR‐200c is evaluated by qPCR. Data are normalized to beta actin (ACTB) expression. All values are average of triplicate experiments, with error bars indicating SEM (*p < 0.05; **p < 0.01)