FIGURE 3.

FAM83A exerts its oncogenic functions in LUAD. (a,b) FAM83A expression was knocked‐down using two siRNAs, and quantitative reverse transcription PCR (qRT‐PCR) was performed to detect the FAM83A expression levels. CCK‐8 assay (c–d), migration and invasion assays (e–f), and western blotting analysis were performed to detect FAM83A expression in A549 and PC9 cells treated with the siRNAs. (g) FAM83A mRNA expression in LUAD was obtained from TCGA database. (h,i) The OS and PFS of the 478 LUAD patients with high and low FAM83A expression levels were analyzed. *p < 0.05; **p < 0.01; ***p < 0.001. Scale bar, 100 μm