Table 3.
Statistical analysis of PD and analgesic parameters
| AUEC28 ratio, % (90% CI) | Emax ratio, % (90% CI) | ||
|---|---|---|---|
| Plasma cortisol | 116 (88–154) | 97 (73–128) | |
| Blood glucose | 101 (96–106) | 61 (26–143) | |
| WBC count | 103 (93–114) | 103 (83–127) | |
| Leg NPRS | Average | 70 (47–105) | — |
| Current | 62 (42–93) | — | |
| Worst | 67 (46–99) | — | |
| Lower-back NPRS | Average | 74 (51–106) | — |
| Current | 78 (52–116) | — | |
| Worst | 75 (54–105) | — | |
Abbreviations: PD, pharmacodynamic; AUEC28, area under the effect curve over 28 days; Emax, maximum effect; NPRS, numeric pain-rating scale; WBC, white blood cell.