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. 2021 Mar 18;25(10):4721–4731. doi: 10.1111/jcmm.16433

FIGURE 5.

FIGURE 5

ILC3 are important players in acute arthritis. A, Synovial MPO (in ng/mL) and B, IL‐22 (in pg/mL), C, Ankle thickness (in mm) and D, Inflammation score (in arbitrary units, AU) were determined in control (following PBS injection) wild type (C57Bl/6) mice or upon K/BxN serum transfer in C57Bl/6, Rag‐2 KO, RORc KO, RORc KO; Rag‐2, Il‐2Rγc mutants (RAGγc) and Ahr f/f; Rorc‐Cre mice. E. representative picture of a FACS analysis showing GFP + cells harvested from the joints of control (C57Bl/6) non‐injected mice and Rorc‐GFP transgenic animals without or upon K/BxN serum injection at day 4. Mean values ± standard deviation are shown (n = 6 mice/group). Representative data from two independent experiments are shown. Data were analysed following a Mann‐Whitney U test. *P <.05**P <.01. SSCside scatter