FIGURE 3.
Smad3 deficiency inhibits cardiac collagen I and collagen III accumulation in db/db mice. A‐C, Western blot and quantitative analysis of collagen I and collagen III. D, E, Real‐time PCR analysis of collagen I and collagen III mRNA expression. Values are expressed as mean ± SE for group of eight mice. *P <.05, **P <.01 and ***P <.001 compared with Smad3 (S3) WT‐db/m group; # P <.05 and ## P <.01 compared with Smad3 (S3) WT‐db/db and Smad3+/−db/db groups